Protein Modification Ontology (MOD)

Name: Protein Modification Ontology (MOD)
Published: 2026-11-13T13:50:45.374984Z

Selected English labels and exact synonyms from the Protein Modification Ontology (MOD), retrieved 2026-11-07, with source identifiers and spelling preserved. Licensed CC BY 4.0; full attribution is listed under Sources. Under semantic review; not endorsed by the ontology's maintainers.

Curator: Oliver Bennett

Languages shown reflect this page; source translations may cover only some concepts.

English
selenium containing residueUnrated SeResUnrated
(2-aminosuccinimidyl)acetic acidUnrated (2-aminosuccinimidyl)acetic acid (Asn)Unrated (3-amino-2,5-dioxo-1-pyrrolidinyl)acetic acidUnrated [(3S)-3-amino-2,5-dioxopyrrolidin-1-yl]acetic acidUnrated anhydroaspartyl glycineUnrated aspartimide glycineUnrated CROSSLNK (2-aminosuccinimidyl)acetic acid (Asn-Gly)Unrated N-(2-aminosuccinyl)glycineUnrated
cysTMT6plex-131 reporter+balance reagent cysteine disulfideUnrated S-(2-{3-[2-(2,6-dimethylpiperidin-1-yl)acetamido]propanamido}ethyl)sulfanylUnrated
PorphResUnrated porphyrin modified residueUnrated
(6S,9aS)-6-(hydroxymethyl)-3-[(1Z,4E,6E,8E)-1-hydroxy-3-oxodeca-1,4,6,8-tetraen-1-yl]-9a-methyl-5,6-dihydro-2H-furo[3,2-g]isochromene-2,9(9aH)-dioneUnrated Deep PurpleUnrated epicocconone derivatized residueUnrated LavaPurpleUnrated Lightning FastUnrated
6'-fluoro-L-tryptophanUnrated 6-fluorotryptophanUnrated
CARBOHYD N-linked (Lac) (glycation) lysineUnrated lactose glycated lysineUnrated
(alpha)- ([([(5S)-5-amino-5-carboxypentyl]amino)propyl][(methyl)amino])-(omega)-methyl poly[propane-1,3-diyl(methylimino)]Unrated lysine derivative Lys(x)Unrated MOD_RES N6-poly(methylaminopropyl)lysineUnrated N6-[3-([(omega)-(dimethyl)aminopropyl-poly(3-[methylamino]propyl)]amino)propyl]lysineUnrated N6-propylamino-poly(propylmethylamino)-propyldimethylamine-L-lysineUnrated silaffin polycationic lysine derivativeUnrated
DcbUnrated dichlorobenzylUnrated
Michael addition of BHT quinone methide to histidineUnrated
MOD_RES N6-(2-hydroxyisobutyryl)lysineUnrated N6-(2-hydroxyisobutanoyl)-L-lysineUnrated
2-azanyl-3-hydroxy-4-butanediamic acidUnrated (2S,3R)-2,4-diamino-3-hydroxy-4-oxobutanoic acidUnrated (2S,3R)-2-amino-3-hydroxy-4-butanediamic acidUnrated (2S,3R)-3-hydroxyasparagineUnrated (3R)3HyAsnUnrated erythro-beta-hydroxylated L-asparagineUnrated L-erythro-beta-hydroxyasparagineUnrated MOD_RES (3R)-3-hydroxyasparagineUnrated
Applied Biosystems cleavable ICAT(TM) lightUnrated icatlightUnrated
(79)Br and (81)Br labeled 3',5'-dibromotyrosineUnrated
Deoxyhexoses (Fuc, Rha)Unrated deoxyhexosylated residueUnrated dHexUnrated
ubiquitination signature tetrapeptidyl lysineUnrated
N-heptosyl-L-asparagineUnrated
arachidonoylated residueUnrated
(2S)-2-amino-5-([2-(5-hydroxy-1H-indol-3-yl)ethyl]amino)-5-oxopentanoic acidUnrated 5-glutamyl serotoninUnrated N2-(gamma-glutamyl)-5-hydoxytryptamineUnrated N5-[2-(5-hydroxy-3-indolyl)ethyl]glutamineUnrated
2-pyrrolidone-5-carboxylic acidUnrated PyrGluUnrated
MbzlUnrated MobUnrated p-methoxybenzyl modified residueUnrated
fluorescein-5-thiosemicarbazide - site CUnrated
2-aminopentanedioic acid 5-methyl esterUnrated (2S)-2-amino-5-methoxy-5-oxopentanoic acidUnrated 5-methyl esterified L-glutamic acidUnrated 5-methyl L-2-aminoglutarateUnrated 5-methyl L-glutamateUnrated (5)-methyl L-hydrogen glutamateUnrated glutamic acid 5-methyl esterUnrated glutamic acid gamma-methyl esterUnrated L-glutamic acid 5-methyl esterUnrated O5MeGluUnrated O-methyl GlutamylUnrated
O-[S-(carboxamidomethyl)phosphopantetheine]-L-serineUnrated
thiophosphate labeled with biotin-HPDP - site YUnrated
benzyloxymethyl modified residueUnrated BomUnrated
(2R)-2-amino-3-[8alpha-riboflavin 5'-(trihydrogen diphosphate) 5'->5'-ester with adenosine]sulfanylpropanoic acidUnrated 8alpha-(S-cysteinyl)FADUnrated MOD_RES S-8alpha-FAD cysteineUnrated S8aFADCysUnrated S-(8alpha-FAD)-L-cysteineUnrated
(2S)-2-amino-5-(N-methylcarbamimidamido)pentanoic acidUnrated delta-N-methylarginineUnrated MOD_RES N5-methylarginineUnrated N5-carbamimidoyl-N5-methyl-L-ornithineUnrated N5Me1ArgUnrated N5-methylated L-arginineUnrated N5-methyl-L-arginineUnrated
N6-stearoyl-L-lysineUnrated
SucPhencarb LysylUnrated
4-(1-hydroxyethyl)-7-isoleucino-2-(threonin-O3-ylcarbonyl)-7,8-dihydroquinolin-8-olUnrated (7R,8S)-7-[(1S,2S)-1-carboxy-2-methylbutyl]amino-2-([(1S,2R)-1-amino-1-carboxypropan-2-yl]oxy)carbonyl-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7,8-dihydroquinolineUnrated BINDING 4-(1-hydroxyethyl)-7,8-dihydroquinolin-8-ol (covalent; via 2 links)Unrated
L-serine removalUnrated
(4-methylpiperazin-1-yl)acetylUnrated mTRAQ reporter+balance reagent acylated residueUnrated
2,6-bis(azanyl)hexanoic acidUnrated (2S)-2,6-diaminohexanoic acidUnrated 6-amino-L-norleucineUnrated ACT_SITE Schiff-base intermediate with substrateUnrated alpha,epsilon-diaminocaproic acidUnrated L-lysineUnrated L-lysine residueUnrated LysUnrated
2-azanyl-4-methylpentanoic acidUnrated (2S)-2-amino-4-methylpentanoic acidUnrated 4-methyl-norvalineUnrated alpha-amino-gamma-methylvaleric acidUnrated alpha-aminoisocaproic acidUnrated LeuUnrated L-leucineUnrated L-leucine residueUnrated
(2S)-2-amino-3-(4-[8alpha-riboflavin 5'-(trihydrogen diphosphate) 5'->5'-ester with adenosine]oxyphenyl)propanoic acidUnrated 8alpha-(O4'-tyrosyl)FADUnrated MOD_RES O-8alpha-FAD tyrosineUnrated O4'-(8alpha-FAD)-L-tyrosineUnrated O8aFADTyrUnrated O-8 alpha-Flavin [FAD])- (of Tyrosine)Unrated
Cl1ResUnrated monochlorinated residueUnrated
4-methyl-1-methylidenepiperazin-1-iumUnrated iTRAQ8plex-114 reporter fragmentUnrated
(18)O isotope tagged reagentUnrated
2-(3-carbamoyl-1-imino-propyl)-1-carboxymethyl-1-imidazolin-5-oneUnrated [2-(3-carbamoyl-1-imino-propyl)-5-oxo-4,5-dihydro-imidazol-1-yl]-acetic acidUnrated [2-(4-amino-4-oxobutanimidoyl)-5-oxo-4,5-dihydro-1H-imidazol-1-yl]acetic acidUnrated 2-imino-glutamine 5-imidazolinone glycineUnrated 2,N-didehydroglutaminyl-5-imidazolinone glycineUnrated CROSSLNK 2-iminomethyl-5-imidazolinone (Gln-Gly)Unrated fluorescent protein FP583 chromophoreUnrated para-hydroxybenzylidene-imidazolidinone chromophoreUnrated red fluorescent protein chromophoreUnrated
3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoylUnrated TMT6plex-129 reporter+balance reagent acylated N-terminalUnrated
1-(L-tryptophan-3-yl)-L-tryptophanUnrated 1'-(L-tryptophan-3'-yl)-L-tryptophanUnrated 2-amino-3-[2-[2-amino-3-(2-carboxyethyl)-1H-indol-4-yl]-1H-indol-3-yl]propanoic acidUnrated (2S,2'S)-3,3'-(3'H-1,3'-biindole-3,3'-diyl)bis(2-aminopropanoic acid)Unrated 3-[2-azanyl-2-carboxyethyl]-3-(3-[2-azanyl-2-carboxyethyl]-1H-indol-2-yl)-1H-indoleUnrated 3-[(2S)-2-amino-2-carboxyethyl]-3-(3-[(2S)-2-amino-2-carboxyethyl]-1H-indol-2-yl)-1H-indoleUnrated ditryptophanUnrated
2-amino-3-(3,7,11-trimethyl-2,6,10-dodecatrienylthio)propanoic acidUnrated (2R)-2-amino-3-([(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]sulfanyl)propanoic acidUnrated farnesylationcUnrated LIPID S-farnesyl cysteineUnrated SFarnCysUnrated S-farnesyl CystenylUnrated S-farnesyl-L-cysteineUnrated
protonated L-lysine (L-lysinium) residueUnrated
(2S)-2-amino-6-(5'-guanosine phosphonamino)hexanoic acidUnrated 5'-guanylic-N6-L-lysineUnrated 5'phos GuanosylUnrated ACT_SITE N6-GMP-lysine intermediateUnrated epsilon-5'-guanylic-L-lysineUnrated L-lysine monoanhydride with 5'-guanylic acidUnrated lysine guanosine-5'-monophosphateUnrated N6-(5'-guanylyl)-lysineUnrated N6GMPLysUnrated N6-L-lysine 5'-guanosine phosphoramidesterUnrated N6-(phospho-5'-guanosine)-L-lysineUnrated N(zeta)-5'-guanylic-lysineUnrated
alpha-amino-beta-(3-indolyl)propionoic acidUnrated D-TrpUnrated D-tryptophanUnrated MOD_RES D-tryptophanUnrated (R)-2-amino-3-(1H-indol-3-yl)propanoic acidUnrated
quaternary amine labeling reagent heavy form (+3amu) N6-L-lysineUnrated
Cl1TyrUnrated monochlorinated L-tyrosineUnrated
oxidized arginine biotinylated with biotin hydrazideUnrated
[2-(1,3-diamino-3-oxopropyl)-5-oxo-4,5-dihydro-imidazol-1-yl]-acetic acidUnrated (2-[(1S)-1,3-diamino-3-oxopropyl]-5-oxo-4,5-dihydro-1H-imidazol-1-yl)acetic acidUnrated 2-[(S)-1,3-diamino-3-oxopropyl]-1-carboxymethyl-1-imidazolin-5-oneUnrated asparaginyl-5-imidazolinone glycineUnrated CROSSLNK 5-imidazolinone (Asn-Gly)Unrated L-asparagine 5-imidazolinone glycineUnrated para-hydroxybenzylidene-imidazolidinone chromophoreUnrated Zoanthus sp. fluorescent protein FP506 chromophoreUnrated
(2S)-2-amino-6-methylaminohexanoic acidUnrated epsilon-methyllysineUnrated MOD_RES N6-methyllysineUnrated N6Me1LysUnrated N6-methylated L-lysineUnrated N6-methyl-L-lysineUnrated N-methyl LysylUnrated N(zeta)-methyllysineUnrated
N-hydroxysuccinimide (ONSu, OSu)Unrated
SOxyMetUnrated sulfur oxygenated L-methionineUnrated
2-azanyl-6-([4-azanyl-4-carboxybutanoyl]azanyl)hexanoic acidUnrated (2S)-2-amino-6-([(4S)-4-amino-4-carboxybutanoyl]amino)hexanoic acidUnrated 5-glutamyl N6-lysineUnrated N6-(L-isoglutamyl)-L-lysineUnrated N6-(L-isoglutamyl)-L-lysine (Glu)Unrated N alpha -(gamma-Glutamyl)-lysineUnrated N(epsilon)-(gamma-glutamyl)lysineUnrated
amidocarboxymethylcysteineUnrated CamCUnrated CamCysUnrated carbamidomethylcUnrated carbamoylmethylcysteineUnrated Carboxamidomethyl (on Cysteine)Unrated Carboxyamidomethyl CystenylUnrated S-carbamoylmethyl-L-cysteineUnrated S-carboxamidomethyl-L-cysteineUnrated
L-lysyl-poly(ADP-ribose)Unrated MOD_RES Lysyl poly(ADP-ribose)Unrated poly[2'-adenosine 5'-(trihydrogen diphosphate) 5'->5'-ester with 1alpha-D-ribofuranosyl] (2S)-2,6-diaminohexanoateUnrated
Hexadecanoylated residueUnrated palmitoylated residueUnrated PalmitoylationUnrated PamResUnrated
3-amino-1,1,3-propanetricarboxylic acidUnrated 3-azanylpropane-1,1,3-tricarboxylic acidUnrated (3S)-3-aminopropane-1,1,3-tricarboxylic acidUnrated (3S)-3-azanylpropane-1,1,3-tricarboxylic acidUnrated 4-carboxyglutamic acidUnrated 4CbxGluUnrated Carboxy GlutamylUnrated gamma-carboxylated L-glutamic acidUnrated gammacarboxyleUnrated L-gamma-carboxyglutamic acidUnrated MOD_RES 4-carboxyglutamateUnrated
oxazole/thiazole ring crosslinked residuesUnrated
(4-methylpiperazin-1-yl)acetylUnrated iTRAQ8plex-115 reporter+balance reagent N'-derivatized histidineUnrated
2-(dimethylamino)-4-methylvaleric acidUnrated 2-(dimethylazanyl)-4-methylpentanoic acidUnrated (2S)-2-(dimethylamino)-4-methylpentanoic acidUnrated MOD_RES N,N-dimethylleucineUnrated N,N-dimethylleucineUnrated N,N-dimethyl-L-leucineUnrated
(2S)-2-amino-5-[((methylamino)(methylimino)methyl)amino]pentanoic acidUnrated MOD_RES Omega-N-methylated arginineUnrated MOD_RES Symmetric dimethylarginineUnrated N3,N4-dimethylarginineUnrated N5-[(methylamino)(methylimino)methyl]ornithineUnrated NG,N'G-dimethylarginineUnrated NoNo'Me2ArgUnrated omega-N,omega-N'-dimethylated L-arginineUnrated omega-N,omega-N'-dimethyl-L-arginineUnrated symmetric dimethylarginineUnrated symmetric dimethyl-L-arginineUnrated
METAL Iron-sulfur (4Fe-4S)Unrated tris-L-cysteinyl L-glutamin-O6-yl tetrairon tetrasulfideUnrated tris-mu3-sulfido-tris(cysteinato)-1kappaS,2kappaS,3kappaS-glutaminato-4kappaN(5)-tetraironUnrated
iminobiotinylation - site KUnrated
Hex1HexNAc2dHex2 N4-glycosylated asparagineUnrated
(2S)-2-amino-5-(beta-D-glucopyranosyl[imino(methylamino)methyl]amino)pentanoic acidUnrated CARBOHYD N-linked (Glc) arginineUnrated NG-beta-D-glucosylarginineUnrated omega-N-(beta-D-glucosyl)-L-arginineUnrated omega-N-glucosyl-L-arginineUnrated omega-N-glycosyl-L-arginineUnrated
2-amino-3-disulfanylpropanoic acidUnrated 2-amino-3-hydrodisulfidopropanoic acidUnrated 2-amino-3-hydropersulfidopropanoic acidUnrated 2-amino-3-persulfhydrylpropanoic acidUnrated 3-disulfanylalanineUnrated 3-(thiosulfeno)-alanineUnrated ACT_SITE Cysteine persulfide intermediateUnrated L-cysteine persulfideUnrated MOD_RES Cysteine persulfideUnrated (R)-2-amino-3-disulfanylpropanoic acidUnrated S-mercaptocysteineUnrated S-sulfanylcysteineUnrated thiocysteineUnrated
thiolated residueUnrated
XylUnrated xylosylated residueUnrated
2-amino-5-guanidino-3,4-dihydroxypentanoic acidUnrated (2S,3Xi,4Xi)-2-amino-5-carbamimidamido-3,4-dihydroxypentanoic acidUnrated 3,4-dihydroxy-L-arginineUnrated 3,4-dihydroxylated L-arginineUnrated 34Hy2ArgUnrated beta,gamma-dihydroxyarginineUnrated MOD_RES 3,4-dihydroxyarginineUnrated
(2S)-2-amino-3-(beta-D-glucopyranosyloxy)propanoic acidUnrated CARBOHYD O-linked (Glc) serineUnrated CARBOHYD O-linked (Hex)Unrated O3-glucosylserineUnrated OGlcSerUnrated O-glucosyl-L-serineUnrated O-glycosylserineUnrated
(35)Cl labeled 3',5'-dichlorotyrosineUnrated
bis-L-cysteinyl bis-L-histidino diiron disulfideUnrated di-mu-sulfido(bis-S-cysteinyliron)(bis-N3'-histidinoiron)Unrated METAL Iron-sulfur (2Fe-2S)Unrated METAL Iron-sulfur (2Fe-2S); via pros nitrogenUnrated Rieske iron-sulfur cofactorUnrated
3x(2)H labeled N6-acetyl-L-lysineUnrated
pentafluorophenyl modified residueUnrated PfpUnrated
oxidized arginine biotinylated with biotin-LC-hydrazide, reducedUnrated
I1ResUnrated Iodination (of Histidine[C4] or Tyrosine[C3])Unrated monoiodinated residueUnrated
phosphorylation of an hydroxyl amino acid with prompt loss of phosphateUnrated
UnimodUnrated
(4-methylpiperazin-1-yl)acetylUnrated iTRAQ117ntermUnrated iTRAQ4plex-117, mTRAQ heavy, reporter+balance reagent acylated N-terminalUnrated mTRAQ heavy on ntermUnrated
tetrakis-L-glutamato bis-L-N1'-histidino lipid carboxylato manganese iron oxideUnrated
N6-Dansyl derivatized lysineUnrated N6DansylLysUnrated
glycosylphosphorylated residueUnrated
(2S)-2-amino-3-hydroxybutanedioic acidUnrated (2S)-3-hydroxyaspartic acidUnrated 3HyAspUnrated 3-hydroxy-L-aspartic acidUnrated erythro-beta-hydroxylated L-aspartic acidUnrated hydroxylationdUnrated monohydroxylated aspartic acidUnrated
monohydroxylated tryptophanUnrated oxywUnrated
NFoResUnrated N-formylated residueUnrated ntermformylUnrated ntermpepformylUnrated
d4CbxGluUnrated L-gamma-carboxyglutamic acid with neutral loss of carbon dioxideUnrated
lipoconjugated residueUnrated
5x(13)C,1x(15)N labeled L-methionineUnrated
(4-methylpiperazin-1-yl)acetylUnrated mTRAQ light reporter+balance reagent acylated residueUnrated
N2Me3MetUnrated N,N,N-trimethyl-L-methionine (from L-methioninium)Unrated
2-aminopentanedioic acid 5-methyl esterUnrated (2S)-2-amino-5-methoxy-5-oxopentanoic acidUnrated 5-methyl L-2-aminoglutarateUnrated 5-methyl L-glutamateUnrated (5)-methyl L-hydrogen glutamateUnrated deamidated 5-methyl esterified glutamineUnrated glutamic acid 5-methyl esterUnrated glutamic acid gamma-methyl esterUnrated L-glutamic acid 5-methyl esterUnrated L-glutamic acid 5-methyl ester (Gln)Unrated MOD_RES Glutamate methyl ester (Gln)Unrated O5MeGlu(Gln)Unrated
2-acetylamino-3-(4-hydoxyphenyl)propanoic acidUnrated 2-acetylazanyl-3-(4-hydoxyphenyl)propanoic acidUnrated (2S)-2-acetamido-3-(4-hydoxyphenyl)propanoic acidUnrated AcTyrUnrated MOD_RES N-acetyltyrosineUnrated N-acetylated L-tyrosineUnrated N-acetyl-L-tyrosineUnrated N-acetyltyrosineUnrated
METAL Iron-sulfur (4Fe-4S)Unrated tetra-mu3-sulfidotris(S-cysteinyliron)(O4-aspartatoiron)Unrated tris-L-cysteinyl L-aspartato tetrairon tetrasulfideUnrated
S-myristoylated residueUnrated SMyrResUnrated
(2S)-2-amino-3-([(2-aminoethoxy)(hydroxy)phosphoryl]oxy)propanoic acidUnrated MOD_RES O-(2-aminoethylphosphoryl)serineUnrated O-(2-aminoethylphosphoryl)-L-serineUnrated O3-(2-aminoethylphosphoryl)-L-serineUnrated O3-(phosphoethanolamine)-L-serineUnrated serine ethanolamine phosphateUnrated serine ethanolamine phosphodiesterUnrated
2'-alpha-mannosyl-L-tryptophanUnrated 2'-mannosyl-L-tryptophanUnrated (2S)-2-amino-3-(2-beta-D-mannopyranosyl-1H-indol-3-yl)propanoic acidUnrated 2'-tryptophan C-mannosideUnrated C2'ManTrpUnrated CARBOHYD C-linked (Man) tryptophanUnrated
N-butanoylUnrated N-butanoylated residueUnrated N-butanoylationUnrated NButResUnrated N-butyrylUnrated N-butyrylationUnrated
2,3-didehydroalanineUnrated 2-aminoacrylic acidUnrated 2-aminopropenoic acidUnrated 4-methylidene-imidazole-5-one (MIO) active siteUnrated anhydroserineUnrated beta-elim-sUnrated dehydroUnrated dehydroalanineUnrated dehydroalanine (Ser)Unrated DhaUnrated Dha(Ser)Unrated MOD_RES 2,3-didehydroalanine (Ser)Unrated phospholosssUnrated
MOD_RES N6-murein peptidoglycan lysineUnrated N6-[(2R,6S)-2-(N-(N-mureinyl-(R)-alanyl)-(S)-glutamyl)amino-6-amino-6-carboxy-1-oxohex-1-yl]lysineUnrated N6-mureinyl-L-lysineUnrated

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