Protein Modification Ontology (MOD)

Name: Protein Modification Ontology (MOD)
Published: 2026-11-13T13:50:45.374984Z

Selected English labels and exact synonyms from the Protein Modification Ontology (MOD), retrieved 2026-11-07, with source identifiers and spelling preserved. Licensed CC BY 4.0; full attribution is listed under Sources. Under semantic review; not endorsed by the ontology's maintainers.

Curator: Oliver Bennett

Languages shown reflect this page; source translations may cover only some concepts.

English
MOD_RES O-(5'-phospho-RNA)-tyrosineUnrated O4'-L-tyrosine 5'-RNA phosphodiesterUnrated O4'-(phospho-5'-RNA)-L-tyrosineUnrated (S)-2-amino-3-[4-(5'-ribonucleic acid phosphonoxy)phenyl]propanoic acidUnrated
sulfonation of N-terminalUnrated
crosslinked residuesUnrated XLNK-Res-ResUnrated
Hex2HexNAc2 N4-glycosylated asparagineUnrated
4-sulfophenyl isothiocyanate derivatized residueUnrated
2-(acetylamino)propanoic acidUnrated 2-(acetylazanyl)propanoic acidUnrated (2S)-2-(acetamido)propanoic acidUnrated AcAlaUnrated acetylalanineUnrated MOD_RES N-acetylalanineUnrated N-acetylated L-alanineUnrated N-acetyl-L-alanineUnrated
N-ethyl iodoacetamide-Unrated
2-aminobutanedioic acid 4-methyl esterUnrated (2S)-2-amino-4-methoxy-4-oxobutanoic acidUnrated 4-methyl L-2-aminosuccinic acidUnrated 4-methyl L-aspartateUnrated 4-methyl L-hydrogen aspartateUnrated aspartic acid 4-methyl esterUnrated aspartic acid beta-methyl esterUnrated L-aspartic acid 4-methyl esterUnrated meesterdUnrated O4MeAspUnrated
2-([(1R)-1-amino-1-carboxyeth-2-yl]sulfanyl)carbonyl-3-methyl-4-([(1S)-1-amino-1-carboxy-4-oxobutan-4-yl]oxy)methyl-1H-indoleUnrated 2-(cystein-S-ylcarbonyl)-3-methyl-4-(glutam-5-yloxy)methylindoleUnrated 2-(cystein-S-ylcarbonyl)-4-[(glutam-5-yloxy)methyl]-3-methyl-1H-indoleUnrated BINDING 3-methyl-4-hydroxymethylindole-2-carboxylic acid (covalent; via 2 links)Unrated
2-ketobutyric acidUnrated 2-oxobutanoic acidUnrated 2-oxobutyric acidUnrated MOD_RES 2-oxobutanoic acidUnrated
3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoylUnrated TMT6plex-130 reporter+balance reagent N'-acylated histidineUnrated
Ac1ResUnrated Acetylation (N terminus, N epsilon of Lysine, O of Serine) (Ac)Unrated monoacetylated residueUnrated
N6Me3LysUnrated N6,N6,N6-trimethyl-L-lysine (from L-lysinium residue)Unrated trimethylkUnrated
(4-methylpiperazin-1-yl)acetylUnrated iTRAQ4plex-114 reporter+balance reagent O3-acylated serineUnrated
(18)O labeled deglycosylated asparagineUnrated
malondialdehyde lysine adduct (+54 amu)Unrated
Beta mercaptoethanol adductUnrated cysteine mercaptoethanolUnrated
1-amino-2-hydroxypropaneUnrated 1-amino-2-propanolUnrated 1-methyl-2-aminoethanolUnrated 2-amino-1-methylethanolUnrated 2-hydroxy-1-propylamineUnrated 2-hydroxypropanamineUnrated 2-hydroxypropylamineUnrated (2R)-1-aminopropan-2-olUnrated alpha-aminoisopropyl alcoholUnrated dCbxThrUnrated decarboxylated threonineUnrated isopropanolamineUnrated MOD_RES Decarboxylated threonineUnrated threamineUnrated
LIPID Phosphatidylethanolamine amidated glycineUnrated N-glycyl-1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamineUnrated N-glycyl-1-(phosphatidyl)ethanolamineUnrated (R)-1-hexadecanoyloxy-2-((Z)-9-octadecenoyloxy)-3-[2-(aminoacetylamino)ethyloxyphospho]propaneUnrated
(2R)-2-amino-3-[(beta-D-glucopyranosyl)sulfanyl]propanoic acidUnrated CARBOHYD S-linked (Glc) cysteineUnrated S-(beta-D-glucopyranosyl)cysteineUnrated SGlcCysUnrated S-glucosyl-L-cysteineUnrated S-glycosyl-cysteineUnrated
sulfated residueUnrated SulfResUnrated Sulphonation (SO3H) (of PMC group)Unrated
4-PECUnrated Pyridylethyl CystenylUnrated S-[2-(pyridin-4-yl)ethyl]-L-cysteineUnrated S-(pyridin-4-ylethyl)-L-cysteineUnrated
RedResUnrated reduced residueUnrated
NleUnrated norleucine residue (Nle)Unrated
2-[1-(N3'-histidyl)ethyl]protoporphyrin IXUnrated 3'-heme-L-histidineUnrated [7-ethenyl-12-((S)-1-[((R)-2-amino-2-carboxyethyl)-3H-imidazol-3-yl]ethyl)-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-bis(2-carboxyethyl)-N21,N22,N23,N24]-ferrateUnrated BINDING Heme (covalent; via pros nitrogen)Unrated N3'-histidyl hemeUnrated N(delta)-histidyl hemeUnrated N(pi)-histidyl hemeUnrated pros-histidyl hemeUnrated
5'phos GuanosylUnrated guanylated residueUnrated
2-[1-azanyl-2-hydroxypropyl]-4,5-dihydro-1,3-thiazole-4-carboxylic acidUnrated (4S)-2-[(1S,2R)-1-amino-2-hydroxypropyl]-4,5-dihydro-1,3-thiazole-4-carboxylic acidUnrated CROSSLNK (4S)-thiazoline-4-carboxylic acid (Thr-Cys)Unrated L-threonine (4S)-thiazoline-4-carboxylic acidUnrated L-threonine thiazoline-4-carboxylic acidUnrated
decarboxylated residueUnrated
ACT_SITE O-(3'-phospho-DNA)-tyrosine intermediateUnrated O4'-L-tyrosine 3'-DNA phosphodiesterUnrated O4'-(phospho-3'-DNA)-L-tyrosineUnrated (S)-2-amino-3-[4-(3'-deoxyribonucleic acid phosphonoxy)phenyl]propanoic acidUnrated
L-cysteinyl-L-selenocysteineUnrated
N-ethyl iodoacetamide-d0 - site CUnrated
deuterium trisubstituted residueUnrated D(H)3ResUnrated
alpha-N-gluconoylated L-histidineUnrated
cysTMT6plex-126 reporter+balance reagent cysteine disulfideUnrated S-(2-{3-[2-(2,6-dimethylpiperidin-1-yl)acetamido]propanamido}ethyl)sulfanylUnrated
crosslinked L-tyrosine residueUnrated XlnkTyrUnrated
modified L-lysine residueUnrated ModLysUnrated
2-amino-3-hydroselenosulfidopropanoic acidUnrated 2-amino-3-hydroselenylsulfidopropanoic acidUnrated 2-amino-3-hydroselenylthiopropanoic acidUnrated ACT_SITE S-selanylcysteine intermediateUnrated MOD_RES S-selenylcysteineUnrated (R)-2-amino-3-(selanylsulfanyl)propanoic acidUnrated S-selanylcysteineUnrated S-selanyl-L-cysteineUnrated S-selenylcysteineUnrated S-selenyl-L-cysteineUnrated
deuterium disubstituted residueUnrated D(H)2ResUnrated
(4-methylpiperazin-1-yl)acetylUnrated iTRAQ8plex-115 reporter+balance reagent O3-acylated serineUnrated
(4-methylpiperazin-1-yl)acetylUnrated iTRAQ8plex-113 reporter+balance reagent acylated residueUnrated
N-heptosyl-L-arginineUnrated
(2S,3R)-2-amino-3-hydroxybutanamideUnrated amidated L-threonineUnrated L-threonine amideUnrated MOD_RES Threonine amideUnrated threoninamideUnrated ThrNUnrated
(2S)-2-amino-3-[(2,4-diacetamido-2,4-dideoxy-beta-D-glucopyranosyl)oxy]propanoic acidUnrated CARBOHYD O-linked (DADDGlc) serineUnrated DADDGlcUnrated O-[2,4-bis(acetylamino)]glucosyl-L-serineUnrated O-(2,4-diacetamido-2,4-dideoxy-beta-D-glucopyranosyl)-L-serineUnrated O-(2,4-diacetamido-2,4-dideoxy-D-glucosyl)-L-serineUnrated O-(2,4-diacetamido-2,4-dideoxyglucosyl)-L-serineUnrated O3-(2,4-diacetamido-2,4-dideoxy-beta-D-glucopyranosyl)-L-serineUnrated O-seryl-beta-2,4-bis(acetylamino)glucosideUnrated
amidination of lysines or N-terminal amines with methyl acetimidate - site KUnrated
2-formamido-4-(methylsulfanyl)butanoic acidUnrated 2-formylamino-4-(methylthio)butanoic acidUnrated 2-formylazanyl-4-(methylsulfanyl)butanoic acidUnrated (2S)-2-formylamino-4-(methylsulfanyl)butanoic acidUnrated MOD_RES N-formylmethionineUnrated NFoMetUnrated N-formylated L-methionineUnrated N-formyl-L-methionineUnrated N-formyl-L-methionine (Met)Unrated
3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoylUnrated TMT6plex-130 reporter+balance reagent acylated residueUnrated
Bruker Daltonics SERVA-ICPL(TM) quantification chemistry, light form - site KUnrated
dihydroxylated leucineUnrated Hy2LeuUnrated
(4-methylpiperazin-1-yl)acetylUnrated iTRAQ4plex-115 reporter+balance reagent O3-acylated serineUnrated
Hex3HexNAc2P1 N4-glycosylated asparagineUnrated
(1Z,2S)-2-carboxy-1-[(3R,4R)-3,4-dihydroxy-5-(phosphonooxy)pentylidene]pyrrolidiniumUnrated N-(DNA-1',2'-dideoxyribos-1'-ylidene)-L-proliniumUnrated
3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoylUnrated TMT6plex-130 reporter+balance reagent N6-acylated lysineUnrated
aldohexosyl lysylUnrated
6x(13)C labeled L-lysineUnrated lys-13c6Unrated
ONbUnrated p-nitrobenzyl ester modified residueUnrated
pyridyl alanylUnrated
Hex3HexNAc2 N4-glycosylated asparagineUnrated (Hex)3-HexNAc-HexNAcUnrated
2-(L-cystein-S-yl)-D-asparagineUnrated (2S)-2,4-diamino-2-([(2R)-2-amino-2-carboxyethyl]sulfanyl)-4-oxobutanoic acidUnrated alpha-(L-cystein-S-yl)-D-asparagineUnrated
disulfide conjugated residueUnrated S-thiolationUnrated
3x(12)C labeled N6-propanoyl-L-lysineUnrated
2-(2-aminosuccinimidyl)-3-sulfanylpropanoic acidUnrated
cyclohexyl esterUnrated OcHexUnrated
2-amino-3-[4-(5-[(2S)-2-amino-2-carboxyethyl]-2-hydroxyphenoxy)phenyl]propanoic acidUnrated (2S)-2-amino-3-[3-(4-[(2S)-2-amino-2-carboxyethyl]phenoxy)-4-hydroxyphenyl]propanoic acidUnrated 3'-(L-tyros-O4'-yl)-L-tyrosineUnrated 3'-(O4'-L-tyrosinyl)-L-tyrosineUnrated CROSSLNK Isodityrosine (Tyr-Tyr)Unrated IsodiTyr (Crosslink)Unrated isodityrosineUnrated O-(5-(2-amino-2-carboxyethyl)-2-hydroxyphenyl)-L-tyrosineUnrated
2-azanyl-6-([4-azanyl-4-carboxybutanoyl]azanyl)hexanoic acidUnrated (2S)-2-amino-6-([(4S)-4-amino-4-carboxybutanoyl]amino)hexanoic acidUnrated 5-glutamyl N6-lysineUnrated N6-(L-isoglutamyl)-L-lysineUnrated N alpha -(gamma-Glutamyl)-lysineUnrated N(epsilon)-(gamma-glutamyl)lysineUnrated
6x(13)C labeled 4-sulfophenyl isothiocyanate derivatized lysineUnrated
(4-methylpiperazin-1-yl)acetylUnrated iTRAQ8plex-118 reporter+balance reagent N'-acylated histidineUnrated
crosslinked glycine residueUnrated XlnkGlyUnrated
HgResUnrated mercury containing modified residueUnrated
(2S)-2-amino-4-oxo-4-[8alpha-riboflavin 5'-(trihydrogen diphosphate) 5'->5'-ester with adenosine]oxybutanoic acidUnrated 8alpha-[(4-aspartyl)oxy]FADUnrated O4-(8alpha-FAD)-L-aspartateUnrated
(4-methylpiperazin-1-yl)acetylUnrated iTRAQ4plex-114 reporter+balance reagent O3-acylated threonineUnrated
deuterium tetrasubstituted residueUnrated D(H)4ResUnrated
cysTMT6plex-130 reporter+balance reagent cysteine disulfideUnrated S-(2-{3-[2-(2,6-dimethylpiperidin-1-yl)acetamido]propanamido}ethyl)sulfanylUnrated
2-amino-3-amidinosulfanylpropanoic acidUnrated 2-amino-3-amidinothiopropanoic acidUnrated (2R)-2-amino-3-(carbamimidoylsulfanyl)propanoic acidUnrated ACT_SITE Amidino-cysteine intermediateUnrated alpha-amino-beta-amidinothiopropionic acidUnrated beta-amidinothioalanineUnrated beta-(S-isothiourea)alanineUnrated S-amidinocysteineUnrated S-amidino-L-cysteineUnrated
sulfonyl halide reagent derivatized residueUnrated
pterin modified residueUnrated PterResUnrated
oxidized lysine biotinylated with biotin hydrazideUnrated
3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoylUnrated TMT6plex-128 reporter+balance reagent acylated N-terminalUnrated
urmylated lysineUnrated
2-amino-3-carboxybutanedioic acidUnrated (2S)-2-aminoethane-1,1,2-tricarboxylic acidUnrated 3-carboxyaspartic acidUnrated 3-carboxy-L-aspartic acidUnrated 3CbxAspUnrated beta-carboxyaspartic acidUnrated gammacarboxyldUnrated L-beta-carboxyaspartic acidUnrated
(4-methylpiperazin-1-yl)acetylUnrated iTRAQ4plex-115 reporter+balance reagent acylated residueUnrated
peptidoglycanated residueUnrated
modification reporter fragmentUnrated
crosslinked L-threonine residueUnrated XlnkThrUnrated
quaternary amine labeling reagent heavy form (+9amu) (N-term & K)Unrated
metal or metal cluster coordinated L-cysteine residueUnrated
crosslinked L-glutamic acid residueUnrated XlnkGluUnrated
(2S,3R)-2-amino-3-methoxybutanoic acidUnrated MOD_RES O-methylthreonineUnrated OMeThrUnrated O-methyl-L-threonineUnrated O-methyl threonineUnrated threonine methyl etherUnrated
2-amino-4-(methylthio)butanoic acidUnrated 2-amino-4-(methylthio)butyric acidUnrated 2-azanyl-4-(methylsulfanyl)butanoic acidUnrated (2S)-2-amino-4-(methylsulfanyl)butanoic acidUnrated alpha-amino-gamma-methylmercaptobutyric acidUnrated alpha-amino-gamma-methylthiobutyric acidUnrated gamma-methylthio-alpha-aminobutyric acidUnrated L-(-)-methionineUnrated L-methionineUnrated L-methionine residueUnrated MetUnrated S-methyl-L-homocysteineUnrated
Michael addition of hydroxymethylvinyl ketone to cysteineUnrated
LIPID N-myristoyl glycineUnrated N-(1-oxotetradecyl)glycineUnrated N-(C14:0 aliphatic acyl)glycineUnrated NMyrGlyUnrated N-myristoylated glycineUnrated N-myristoyl-glycineUnrated N-myristoylglycineUnrated N-myristylglycineUnrated ntermpepmyristoylationgUnrated N-tetradecanoylglycineUnrated (tetradecanoylamino)ethanoic acidUnrated
MeArgUnrated methylated arginineUnrated
AcCysUnrated monoacetylated L-cysteineUnrated
tetra-mu3-sulfidotris(S-cysteinyliron)(O3-serinyliron)Unrated tris-L-cysteinyl L-serinyl tetrairon tetrasulfideUnrated
(4-methylpiperazin-1-yl)acetylUnrated iTRAQ8plex-114 reporter+balance reagent O3-acylated serineUnrated
2-amino-6-(ADP-ribosyl)amino-hexanoic acidUnrated epsilon-ADP-ribosyllysineUnrated MOD_RES N6-(ADP-ribosyl)lysineUnrated N6-(ADP-ribosyl)-L-lysineUnrated N6-[alpha-D-ribofuranoside 5'->5'-ester with adenosine 5'-(trihydrogen diphosphate)]-L-lysineUnrated N6-alpha-D-ribofuranosyl-L-lysine 5'->5'-ester with adenosine 5'-(trihydrogen diphosphate)Unrated N(zeta)-ADP-ribosyllysineUnrated (S)-2-amino-6-([adenosine 5'-(trihydrogen diphosphate) 5'->5'-ester with alpha-D-ribofuranosyl]amino)hexanoic acidUnrated
cysTMT6plex-128 reporter+balance reagent cysteine disulfideUnrated S-(2-{3-[2-(2,6-dimethylpiperidin-1-yl)acetamido]propanamido}ethyl)sulfanylUnrated
N6-[3-(carboxamidomethylthio)propanoyl]lysineUnrated
O-octanoylated residueUnrated OOctResUnrated
1-(cystein-S-yl)-glycinateUnrated (2R)-2-amino-3-[(aminoacetyl)sulfanyl]propanoic acidUnrated glycine cysteine thioesterUnrated MOD_RES CysO-cysteine adductUnrated S-(2-amino-1-oxoethyl)cysteineUnrated S-(glycyl)-L-cysteineUnrated S-(glycyl)-L-cysteine (Gly)Unrated
(4-methylpiperazin-1-yl)acetylUnrated iTRAQ8plex-119 reporter+balance reagent N'-acylated histidineUnrated

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