Protein Modification Ontology (MOD)

Name: Protein Modification Ontology (MOD)
Published: 2026-11-13T13:50:45.374984Z

Selected English labels and exact synonyms from the Protein Modification Ontology (MOD), retrieved 2026-11-07, with source identifiers and spelling preserved. Licensed CC BY 4.0; full attribution is listed under Sources. Under semantic review; not endorsed by the ontology's maintainers.

Curator: Oliver Bennett

Languages shown reflect this page; source translations may cover only some concepts.

English
methionine oxidation with neutral loss of 64 DaUnrated
1,2-ethanedithiol (EDT)Unrated 1,2-ethanedithiol modified residueUnrated
N6-(2,2,5,7,8-pentamethylchroman-6-sulfonyl)-L-lysineUnrated PmcLysUnrated PMC lysylUnrated
ManUnrated mannosylated residueUnrated
1'-(phospho-5'-guanosine)-L-histidineUnrated (2S)-2-amino-3-(1-(5'-adenosine phosphono)imidazol-4-yl)propanoic acidUnrated ACT_SITE GMP-histidine intermediateUnrated L-histidine 5'-guanosine phosphoramidesterUnrated L-histidine monoanhydride with 5'-guanylic acidUnrated N1'-guanylylated histidineUnrated N(tau)-5'-guanylic-L-histidineUnrated (phospho-5'-guanosine)-L-histidineUnrated tele-5'-guanylic-L-histidineUnrated
1-[(S)-5-amino-5-carboxypentyl]amino-2-[(S)-2-amino-2-carboxyethyl]-2,6-cyclohexadien-4,5-dioneUnrated 2'-(L-lysine)-L-tyrosyl-4',5'-quinoneUnrated 2'-(L-lys-N6-yl)-L-4',5'-topaquinoneUnrated 5'-(N6-L-lysine)-L-topaquinoneUnrated CROSSLNK Lysine tyrosylquinone (Lys-Tyr)Unrated CROSSLNK Lysine tyrosylquinone (Tyr-Lys)Unrated LTQUnrated lysyl oxidase cofactorUnrated
[2-(1,5-diaminopentanyl)-5-oxo-4,5-dihydro-imidazol-1-yl]-acetic acidUnrated (2-[(1S)-1,5-diaminopentyl]-5-oxo-4,5-dihydro-1H-imidazol-1-yl)acetic acidUnrated 2-[(S)-1,5-diaminopentanyl]-1-carboxymethyl-1-imidazolin-5-oneUnrated Anemonia majano fluorescent protein FP486 chromophoreUnrated CROSSLNK 5-imidazolinone (Lys-Gly)Unrated L-lysine 5-imidazolinone glycineUnrated lysyl-5-imidazolinone glycineUnrated para-hydroxybenzylidene-imidazolidinone chromophoreUnrated
(2R,3S)-2-amino-3-([(2R)-2-amino-2-carboxyethyl]sulfanyl)butanedioic acidUnrated (2R,3S,6R)-2,6-diamino-3-carboxy-4-thiaheptanedioic acidUnrated 3-carboxy-L-lanthionineUnrated 3-(L-cystein-S-yl)-L-aspartic acidUnrated 3-(S-L-cysteinyl)-L-aspartic acidUnrated CROSSLNK 3-cysteinyl-aspartic acid (Cys-Asp)Unrated
di-mu-sulfido(bis-S-cysteinyliron)(S-cysteinyl-O4-aspartatoiron)Unrated METAL Iron-sulfur (2Fe-2S)Unrated tris-L-cysteinyl L-aspartato diiron disulfideUnrated
methionine oxidation with neutral loss of 80 DaUnrated
(2S)-2-amino-3-(alpha-D-galactopyranosyloxy)propanoic acidUnrated CARBOHYD O-linked (Gal) serineUnrated CARBOHYD O-linked (Hex)Unrated O3-galactosylserineUnrated O-galactosyl-L-serineUnrated OGalSerUnrated O-glycosylserineUnrated
(2S,4S)-2-amino-4,5-dihydroxy-4-methylpentanoic acidUnrated (2S,4S)-4,5-dihydroxyleucineUnrated (4S)-4,5-dihydroxyleucineUnrated gamma,delta-dihydroxyleucineUnrated MOD_RES (4S)-4,5-dihydroxyleucineUnrated
2-amino-5,6-dimercapto-7-methyl-3,7,8a,9-tetrahydro-8-oxa-1,3,9,10-tetraazaanthracen-4-one guanosine dinucleotideUnrated bis[8-amino-1a,2,4a,5,6,7,10-heptahydro-2-(trihydrogen diphosphate 5'-ester with guanosine)methyl-6-oxo-3,4-disulfanyl-pteridino[6,7-5,6]pyranoato-S3,S4]-O3-serinyl-molybdenum oxideUnrated L-serinyl molybdenum bis(molybdopterin guanine dinucleotide)Unrated
gamma-glutamylpolyglutamic acidUnrated L-isoglutamyl-polyglutamic acidUnrated
N6-[4-(2-aminoethyl)benzenesulfonyl]lysineUnrated
acetate labeling reagent (N-term) (heavy form, +3amu)Unrated
AbuUnrated alpha-aminobutyric acidUnrated alpha-amino-n-butyric acidUnrated butyrineUnrated dCbxGluUnrated L-2-aminobutanoic acidUnrated L-2-aminobutanoic acid (Glu)Unrated L-2-aminobutyric acidUnrated L-2-amino-n-butyric acidUnrated L-alpha-aminobutyric acidUnrated L-alpha-amino-n-butyric acidUnrated L-butyrineUnrated (S)-2-aminobutanoic acidUnrated
4x(2)H labeled dimethylated residueUnrated
(4-methylpiperazin-1-yl)acetylUnrated iTRAQ4plex-115 reporter+balance reagent O3-acylated threonineUnrated
biantennary (-2 galactose) N4-glycosylated asparagineUnrated
(2S,3S)-2-amino-3-hydroxy-3-(1H-indol-3-yl)propanoic acidUnrated 3-hydroxylated L-tryptophanUnrated 3-hydroxy-L-tryptophanUnrated 3-hydroxytryptophanUnrated 3HyTrpUnrated beta-hydroxytryptophanUnrated MOD_RES 3-hydroxytryptophanUnrated
carboxymethylcUnrated Carboxymethyl cysteineUnrated Carboxymethyl CystenylUnrated CmCUnrated S-carboxymethyl-L-cysteineUnrated
[13-[(S)-(4-amino-4-carboxy)butanoyloxymethyl]-3-[(S)-(3-amino-3-carboxy)propanoyloxymethyl]-12-[(S)-(3-amino-3-carboxy)propylsulfoniumethyl]-7-ethenyl-8,17-dimethyl-21H,23H-porphine-2,18-bis(2-carboxyethyl)-N21,N22,N23,N24]-ferrateUnrated 1,5-bishydroxymethyl protoporphyrin IX 1-glutamate ester 5-aspartate ester 2-methionine sulfoniumUnrated BINDING Heme (covalent; via 3 links)Unrated dihydroxyheme-L-aspartate ester-L-glutamate ester-L-methionine sulfoniumUnrated myeloperoxidase heme cofactorUnrated
2-amino-5,6-dimercapto-7-methyl-3,7,8a,9-tetrahydro-8-oxa-1,3,9,10-tetraazaanthracen-4-one guanosine dinucleotideUnrated bis[8-amino-1a,2,4a,5,6,7,10-heptahydro-2-(trihydrogen diphosphate 5'-ester with guanosine)methyl-6-oxo-3,4-disulfanyl-pteridino[6,7-5,6]pyranoato-S3,S4]-cystein-S-yl-molybdenumUnrated L-cysteinyl molybdenum bis(molybdopterin guanine dinucleotide)Unrated
3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoylUnrated TMT6plex reporter+balance reagent acylated N-terminalUnrated
ModGluUnrated modified L-glutamic acid residueUnrated
Me1ProUnrated monomethylated prolineUnrated
chlorinated residueUnrated ClResUnrated
2-[1-azanyl-2-sulfanylethyl]-4,5-dihydro-1,3-oxazole-4-carboxylic acidUnrated (4S)-2-[(1R)-1-amino-2-sulfanylethyl]-4,5-dihydro-1,3-oxazole-4-carboxylic acidUnrated CROSSLNK Oxazoline-4-carboxylic acid (Cys-Ser)Unrated L-cysteine oxazoline-4-carboxylic acidUnrated
crosslinked D-phenylalanine residueUnrated XlnkDPheUnrated
2-amino-5-formylvaleric acidUnrated 2-aminoadipate 6-semialdehydeUnrated 2-amino-adipic acid semialdahydeUnrated (2S)-2-amino-6-oxohexanoic acidUnrated 5-formyl-norvalineUnrated 6-oxonorleucineUnrated AASAUnrated Allysine (from Lysine)Unrated alpha-amino-adipic acid delta-semialdahydeUnrated L-allysineUnrated LysalUnrated MOD_RES AllysineUnrated Oxidation of lysine (to aminoadipic semialdehyde)Unrated
2,6-dimethyl-1-methylidenepiperidiniumUnrated cysTMT6plex reporter fragmentUnrated TMT6plex reporter fragmentUnrated
ACT_SITE O-(5'-phospho-DNA)-serine intermediateUnrated MOD_RES O-(5'-phospho-DNA)-serineUnrated O3-L-serine 5'-DNA phosphodiesterUnrated O3-(phospho-5'-DNA)-L-serineUnrated O-(phospho-5'-DNA)-L-serineUnrated (S)-2-amino-3-(5'-deoxyribonucleic acid phosphonoxy)propanoic acidUnrated
2,6-dimethyl-1-methylidenepiperidiniumUnrated cysTMT6plex-126 reporter fragmentUnrated TMT6plex-126 reporter fragmentUnrated
GalResUnrated monogalactosylated residueUnrated
RibUnrated ribosylated residueUnrated
dansyl chloride derivatized residueUnrated Dansyl (Dns)Unrated DansylResUnrated
METAL Iron-sulfur (4Fe-4S)Unrated METAL Iron-sulfur (4Fe-4S); via pros nitrogenUnrated tetra-mu3-sulfidotris(S-cysteinyliron)(N3'-histidinoiron)Unrated tris-L-cysteinyl L-N3'-histidino tetrairon tetrasulfideUnrated
2-amino-N4-hydroxymethylbutanediamic acidUnrated (2S)-2-amino-4-[(hydroxymethyl)amino]-4-oxobutanoic acidUnrated beta-hydroxymethylasparagineUnrated N4-hydroxymethylasparagineUnrated N4-hydroxymethyl-L-asparagineUnrated N(gamma)-hydroxymethylasparagineUnrated
alpha-amino monomethylated residueUnrated N2Me1ResUnrated ntermmethylUnrated ntermpepmethylUnrated
N4-hexosaminylated asparagineUnrated
4-methoxy-2,3,6-trimethylbenzenesulfonylUnrated MtrUnrated
2-azanyl-6-([4-azanyl-4-carboxybutanoyl]azanyl)hexanoic acidUnrated (2S)-2-amino-6-([(4S)-4-amino-4-carboxybutanoyl]amino)hexanoic acidUnrated 5-glutamyl N6-lysineUnrated CROSSLNK Isoglutamyl lysine isopeptide (Lys-Gln)Unrated N6-(L-isoglutamyl)-L-lysineUnrated N6-(L-isoglutamyl)-L-lysine (Gln)Unrated N alpha -(gamma-Glutamyl)-lysineUnrated N(epsilon)-(gamma-glutamyl)lysineUnrated XLNK-N6Lys-5Glu(Gln)Unrated
natural, non-standard encoded residueUnrated
modified L-leucine residueUnrated ModLeuUnrated
(2S,3R)-2-amino-3-(6-deoxy-alpha-D-galactopyranosyloxy)butanoic acidUnrated CARBOHYD O-linked (dHex)Unrated CARBOHYD O-linked (Fuc) threonineUnrated O3-fucosylthreonineUnrated O-fucosyl-L-threonineUnrated OFucThrUnrated O-glycosylthreonineUnrated
quaternary amine labeling reagent heavy form (+9amu) N6-L-lysineUnrated
acetaldehyde crosslinked penta-L-lysineUnrated
MOD_RES O-UMP-serineUnrated O-(phospho-5'-uridine)-L-serineUnrated OUMPSerUnrated
(2S)-2-amino-3-(octanoyloxy)propanoic acidUnrated LIPID O-octanoyl serineUnrated L-serine octanoate esterUnrated O3-octanoyl-L-serineUnrated O-octanoylated L-serineUnrated O-octanoyl-L-serineUnrated OOctSerUnrated
(2S)-4-amino-2-formamido-4-oxobutanoic acidUnrated FormylasparagineUnrated N2-Formyl-L-asparagineUnrated Nω-formyl asparagineUnrated
iodinated residueUnrated IResUnrated
4'-fluoro-L-phenylalanineUnrated 4-fluorophenylalanineUnrated para-fluorophenylalanineUnrated p-fluorophenylalanineUnrated rho-fluorophenylalanineUnrated
(4-methylpiperazin-1-yl)acetylUnrated iTRAQ4plex reporter+balance reagent O-acylated residueUnrated
(18)O labeled deamidated residueUnrated
pyruvic acid iminylated residueUnrated
bis[4-(hydroxy[sulfanyl-kappaS]methylidene)-1,3-oxazol-5(4H)-onato-kappaN]copperUnrated METAL copper [Cu-methanobactin OB3b complex]Unrated methanobactin OB3b copper complexUnrated
4-([4-(dimethylamino)phenyl]diazenyl)benzenesulfonylUnrated Dabsyl chloride derivatized residueUnrated DabsylResUnrated
modified L-tyrosine residueUnrated ModTyrUnrated
(4-methylpiperazin-1-yl)acetylUnrated iTRAQ8plex-113 reporter+balance reagent N'-acylated histidineUnrated
L-isoleucine removalUnrated
4-methyl-1-methylidenepiperazin-1-iumUnrated iTRAQ4plex-114 reporter fragmentUnrated
(2S)-2-amino-3-(6-chloro-1H-indol-3-yl)propanoic acidUnrated 6'-chloro-L-tryptophanUnrated 6'-ClTrpUnrated MOD_RES 6'-chlorotryptophanUnrated
imidoester crosslink dimethyl pimelimidate doubly attachedUnrated
(2R,3Xi)-2-amino-3-(methylsulfanyl)butanedioic acidUnrated 3-carboxy-S-methyl-cysteineUnrated 3MeSAspUnrated 3-methylthio-aspartic acidUnrated 3-(methylthio)-L-aspartic acidUnrated beta-methylthio-aspartic acidUnrated beta-Methylthio-aspartic acidUnrated bmethylthioldUnrated L-beta-methylthioaspartic acidUnrated methythioldUnrated MOD_RES 3-methylthioaspartic acidUnrated
N6-(pyridylacetyl)lysineUnrated
2-methylamino-4-(methylthio)butanoic acidUnrated (2S)-2-methylamino-4-(methylsulfanyl)butanoic acidUnrated Methyl MethionylUnrated MOD_RES N-methylmethionineUnrated NMe1MetUnrated N-methylated L-methionineUnrated N-methyl-L-methionineUnrated N-methylmethionineUnrated
2-(1H-imidazolyl)ethaniminiumUnrated phosphohistidine immonium ionUnrated
4aFMNResUnrated 4alpha-FMN modified residueUnrated
phosphorylation to amine thiol - site TUnrated
2-[1-azanyl-2-sulfanylethyl]-1,3-thiazole-4-carboxylic acidUnrated 2-[(1S)-1-amino-2-sulfanylethyl]-1,3-thiazole-4-carboxylic acidUnrated CROSSLNK Thiazole-4-carboxylic acid (Cys-Cys)Unrated L-cysteine thiazole-4-carboxylic acidUnrated
(2S,4R)-2-amino-4,5-dihydroxy-4-methylpentanoic acidUnrated (2S,4R)-4,5-dihydroxyleucineUnrated (4R)-4,5-dihydroxyleucineUnrated gamma,delta-dihydroxyleucineUnrated MOD_RES (4R)-4,5-dihydroxyleucineUnrated
metal or metal cluster coordinated L-selenocysteine residueUnrated
methylthiolated residueUnrated
(4-methylpiperazin-1-yl)acetylUnrated iTRAQ8plex reporter+balance reagent O-acylated residueUnrated
Hex1HexNAc1dHex1 N4-glycosylated asparagineUnrated
(2)H deuterium tagged reagentUnrated
(2R,6S)-2-(N-mureinyl-(R)-alanyl-(S)-isoglutamyl)amino-6-(alanyl-pentaglycyl)amino-pimeloyl-(S)-alanyl-(S)-alanineUnrated L-alanyl-pentaglycyl-murein peptidoglycanUnrated MOD_RES Pentaglycyl murein peptidoglycan amidated alanineUnrated
Pierce EZ-Link Biotin-HPDP modified L-cysteineUnrated
2-azanyl-6-[(4-azanyl-2-hydroxybutyl)azanyl]hexanoic acidUnrated (2S)-2-amino-6-([(2R)-4-amino-2-hydroxybutyl]amino)hexanoic acidUnrated (2S,9R)-2,11-diazanyl-9-hydroxy-7-azaundecanoic acidUnrated (2S,9R)-hypusineUnrated HypuUnrated hypusineUnrated L-hypusineUnrated MOD_RES HypusineUnrated N-(4-NH2-2-OH-butyl)- (of Lysine)Unrated N6-(4-amino-2-hydroxybutyl)-L-lysineUnrated
2-azanyl-3-selanylpropanoic acidUnrated (2R)-2-amino-3-selanylpropanoic acidUnrated 3-selenylalanineUnrated L-selenocysteineUnrated L-selenocysteine (Cys)Unrated NON_STD SelenocysteineUnrated Sec(Cys)Unrated SeCysUnrated selenium cysteineUnrated
metal or metal cluster coordinated L-tyrosine residueUnrated
N-ethyl iodoacetamide-d0 - site YUnrated
3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoylUnrated TMT6plex-129 reporter+balance reagent O4'-acylated tyrosineUnrated
2,5-DihydroxyphenylalanineUnrated 2,5-DioxyphenylalanineUnrated 2-amino-3-(2,5-dihydroxyphenyl)propanoic acidUnrated L-2,5-dihydroxyphenylalanine (Phe)Unrated
alpha-amino morpholine-2-acetylated residueUnrated N-succinimidylmorpholine-2-acetate alpha-amino derivativeUnrated
hexNAcSUnrated O-(2-acetylamino-2-deoxy-beta-D-hexopyranosyl)-L-serineUnrated O3-(2-acetamido-2-deoxy-beta-D-hexopyranosyl)-L-serineUnrated O-glycosylserineUnrated OHexNAcSerUnrated O-(N-acetylamino)hexosyl-L-serineUnrated O-(N-acetylhexosaminyl)serineUnrated O-seryl-beta-N-acetylhexosaminideUnrated (S)-2-amino-3-(2-acetamido-2-deoxy-beta-D-hexopyranosyloxy)propanoic acidUnrated
(4-methylpiperazin-1-yl)acetylUnrated iTRAQ8plex-114 reporter+balance reagent O4'-acylated tyrosineUnrated
2-(p-biphenyl)isopropyl-oxycarbonylUnrated BpocUnrated
4x(2)H labeled alpha-dimethylamino N-terminal residueUnrated mod190Unrated
inositolUnrated
(2S)-2-amino-3-(4,5-dihydroxy-1H-indol-3-yl)propanoic acidUnrated 4,5-DihydroxytryptophanUnrated Double oxidation of TrpUnrated
reduced histidine 4-hydroxynonenal adductUnrated
4-trimethylammoniumbutanoyl derivatized residueUnrated
4'-fluoro-L-tryptophanUnrated 4-fluorotryptophanUnrated
CamCOUnrated S-carbamoylmethyl-L-cysteine sulfoxideUnrated S-carboxamidomethyl-L-cysteine sulfoxideUnrated
hexose glycated L-lysineUnrated
2-azanyl-3-methylbutanoic acidUnrated (2S)-2-amino-3-methylbutanoic acidUnrated alpha-amino-beta-methylbutyric acidUnrated alpha-aminoisovaleric acidUnrated L-valineUnrated L-valine residueUnrated ValUnrated
MOD_RES N6-(beta-hydroxybutyryl)lysineUnrated N6-((3R)-3-hydroxybutanoyl)-L-lysineUnrated
(2)H deuterium labeled residueUnrated

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