Protein Modification Ontology (MOD)

Name: Protein Modification Ontology (MOD)
Published: 2026-11-13T13:50:45.374984Z

Selected English labels and exact synonyms from the Protein Modification Ontology (MOD), retrieved 2026-11-07, with source identifiers and spelling preserved. Licensed CC BY 4.0; full attribution is listed under Sources. Under semantic review; not endorsed by the ontology's maintainers.

Curator: Oliver Bennett

Languages shown reflect this page; source translations may cover only some concepts.

English
4x(12)C, 4x(1)H labeled alpha-amino succinylated residueUnrated
Me1ArgUnrated methylrUnrated monomethylated L-arginineUnrated N-methyl ArginylUnrated
modified L-proline residueUnrated ModProUnrated
6x(13)C,1x(15)N labeled L-isoleucineUnrated
2-azanyl-3-methylpentanoic acidUnrated (2S,3R)-2-amino-3-methylpentanoic acidUnrated 3-methyl-norvalineUnrated allo-L-isoleucineUnrated alpha-amino-beta-methylvaleric acidUnrated L-allo-isoleucineUnrated L-threo-isoleucineUnrated MOD_RES L-allo-isoleucineUnrated
metal or metal cluster coordinated L-aspartic acid residueUnrated
menadione quinone derivative - site KUnrated
(2S)-2-amino-3-((9Z)-9-hexadecenoyloxy)propanoic acidUnrated LIPID O-palmitoleyl serineUnrated L-serine cis-9-hexadecenoate esterUnrated mod186Unrated O3-palmitoleyl-serineUnrated O-palmitoleyl-L-serineUnrated
4-[(4S)-4-amino-4-carboxybutyl]-1-[(5S)-5-amino-5-carboxypentyl]-3,5-bis[(3S)-3-amino-3-carboxypropyl]pyridiniumUnrated 6-[4-(4-amino-4-carboxybutyl)-3,5-bis(3-amino-3-carboxypropyl)pyridinio]norleucineUnrated desmosineUnrated
Carboxymethyl (on Cysteine)Unrated iodoacetic acid derivatized residueUnrated
2-oxopropanoic acidUnrated MOD_RES Pyruvic acid (Cys)Unrated Pyruv(Cys)Unrated pyruvic acidUnrated pyruvic acid (Cys)Unrated
2-[(1S)-1-amino-2-hydroxyethyl]-5-methyl-1,3-oxazoline-4-carboxylic acidUnrated 2-[(1S)-1-amino-2-hydroxyethyl]-5-methyl-4,5-dihydro-1,3-oxazole-4-carboxylic acidUnrated 2-[(1S)-1-azanyl-2-hydroxyethyl]-5-methyl-4,5-dihydro-1,3-oxazole-4-carboxylic acidUnrated CROSSLNK 5-methyloxazoline-4-carboxylic acid (Ser-Thr)Unrated L-serine 5-methyloxazoline-4-carboxylic acidUnrated
2-oxopropanoic acidUnrated MOD_RES Pyruvic acid (Cys)Unrated MOD_RES Pyruvic acid (Ser)Unrated pyruvic acidUnrated
(4-methylpiperazin-1-yl)acetylUnrated mTRAQ light on YUnrated mTRAQ light reporter+balance reagent O4'-acylated tyrosineUnrated
3,3'-diselenobis(2-aminopropanoic acid)Unrated 3,3'-diselenobisalanineUnrated 3,3'-diselenodialanineUnrated beta,beta'-diamino-beta,beta'-dicarboxydiethyldiselenideUnrated beta,beta'-diselenodialanineUnrated bis(alpha-aminopropionic acid)-beta-diselenideUnrated bis(beta-amino-beta-carboxyethyl)diselenideUnrated CROSSLNK Selenocystine (Sec-Sec)Unrated diselenocysteineUnrated L-selenocystineUnrated L-selenocystine (selenium disubstituted L-cystine)Unrated (R,R)-3,3'-diselane-1,2-diylbis(2-aminopropanoic acid)Unrated Se2(S2)Cys2Unrated selenium cystineUnrated
levuglandinyl (prostaglandin H2) adductUnrated
(2S)-2-amino-4-[(R)-methylsulfinyl]butanoic acidUnrated L-methionine (R)-S-oxideUnrated L-methionine (R)-sulfoxideUnrated MOD_RES Methionine (R)-sulfoxideUnrated R-MetOUnrated
Hex1HexNAc1NeuAc1 O-glycosylated serineUnrated
ModGlyUnrated modified glycine residueUnrated
Cy3 CyDye DIGE Fluor saturation dyeUnrated
(2S)-2-amino-6-([(2S)-2,6-diaminohexanoyl]amino)hexanoic acidUnrated N6-(alpha-lysyl)-lysineUnrated N6-(L-lysyl)-L-lysineUnrated
N-phosphorylated residueUnrated NPhosResUnrated
3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoylUnrated cysTMT6plex-131 reporter fragmentUnrated TMT6plex-131 reporter+balance reagent acylated residueUnrated
(2S)-(2-[S-(L-cystein-S-yl)-L-cysteinyl]amino-2-deoxy-alpha-D-glucopyranosyloxy)-butanedioic acidUnrated BSHUnrated L-cysteine bacillithiol disulfideUnrated MOD_RES S-bacillithiol cysteine disulfideUnrated
Br2TyrUnrated dibrominated tyrosineUnrated
ModCysUnrated modified L-cysteine residueUnrated
metal or metal cluster coordinated L-histidine residueUnrated
S-benzyl-L-cysteineUnrated
(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosineUnrated 5'-O-[(3-aminopropoxy)(L-aspart-1-ylamino)phosphoryl]adenosineUnrated 9-(5'-O-[(3-aminopropoxy)(L-aspart-1-ylamino)phosphoryl]-beta-D-ribofuranosyl)adenineUnrated microcin C7 asparagine modificationUnrated MOD_RES Aspartic acid 1-[(3-aminopropyl)(5'-adenosyl)phosphono]amideUnrated N-(aspart-1-yl)-O-(3-aminopropyl)-O-(5'-adenosyl)phosphoramideUnrated
5-imidazolinone ring crosslinked residues (Cys)Unrated
N-arachidonoylated residueUnrated
GSIAspUnrated LIPID GPI-like-anchor amidated aspartateUnrated N-aspartyl-glycosylsphingolipidinositolethanolamineUnrated
2-amino-2-methylbutanoic acidUnrated isovaline residue (Iva)Unrated Isovalyl (-I-,-Iva-)Unrated IvaUnrated
2-amino-5-[(aminoiminomethyl)amino]-3-hydroxypentanoic acid [tautomer]Unrated 2-amino-5-(carbamimidamido)-3-hydroxypentanoic acid [tautomer]Unrated 2-amino-5-guanidino-3-hydroxypentanoic acidUnrated (2S,3R)-2-amino-5-[(diaminomethylidene)amino]-3-hydroxypentanoic acidUnrated (3R)-3-hydroxy-L-arginineUnrated beta-hydroxyarginineUnrated C(beta)-hydroxyarginineUnrated MOD_RES (3R)-3-hydroxyarginineUnrated
(2S)-2-amino-5-([(dimethylamino)(imino)methyl]amino)pentanoic acidUnrated asymmetric dimethylarginineUnrated asymmetric dimethyl-L-arginineUnrated MOD_RES Asymmetric dimethylarginineUnrated MOD_RES Omega-N-methylated arginineUnrated N5-[(dimethylamino)(imino)methyl]ornithineUnrated NG,NG-dimethylarginineUnrated NoNoMe2ArgUnrated omega-N,omega-N-dimethlyated L-arginineUnrated omega-N,omega-N-dimethyl-L-arginineUnrated
dHex1Hex5HexNAc3 N4-glycosylated asparagineUnrated
N4GlycoAsnUnrated N4-glycosyl-L-asparagineUnrated
(18)O label at both C-terminal oxygensUnrated ctermpepdio18Unrated
(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yliumUnrated Farn+Unrated farnesyl cationUnrated farnesyl reporter fragmentUnrated
alpha-amino-Dansyl derivatized residueUnrated N2DansylResUnrated
HexNAc1dHex2 N4-glycosylated asparagineUnrated
1x(13)C,3x(2)H C(6)-labeled L-methionineUnrated
imidoester crosslink dimethyl pimelimidate singly attachedUnrated
L-tyrosine removalUnrated
3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoylUnrated TMT6plex-126 reporter+balance reagent O3-acylated serineUnrated
L-phenylalanine removalUnrated
(2S,3S,4R)-2-amino-3,4-dihydroxy-3-methylpentanoic acidUnrated (2S,3S,4R)-3,4-dihydroxyisoleucineUnrated (3S,4R)-3,4-dihydroxyisoleucineUnrated beta,gamma-dihydroxyisoleucineUnrated MOD_RES (3S,4R)-3,4-dihydroxyisoleucineUnrated
3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoylUnrated TMT6plex-126 reporter+balance reagent O4'-acylated tyrosineUnrated
dehydrogenated residueUnrated dHResUnrated
glycine removalUnrated
(4-methylpiperazin-1-yl)acetylUnrated iTRAQ8plex-117 reporter+balance reagent acylated residueUnrated
Hex1HexNAc1NeuAc1 glycosylated residueUnrated NeuAc-Hex-HexNAcUnrated
2-amino-2-methylpropanoic acidUnrated 2-amino-2-methylpropionic acidUnrated 2-aminoisobutyric acid residue (Aib)Unrated 2-methylalanineUnrated AibUnrated alpha,alpha-dimethylglycineUnrated alpha-aminoisobutyric acidUnrated alpha-methylalanineUnrated
(2S)-2-amino-3-(6-deoxy-alpha-D-galactopyranosyloxy)propanoic acidUnrated CARBOHYD O-linked (dHex)Unrated CARBOHYD O-linked (Fuc)Unrated CARBOHYD O-linked (Fuc) serineUnrated O3-fucosylserineUnrated O-fucosyl-L-serineUnrated OFucSerUnrated O-glycosylserineUnrated
cyclized residueUnrated CycResUnrated
succinyl aspartamylUnrated succinyl beta-aspartyl anhydrideUnrated
3-[(2,6-dimethylpiperidin-1-yl)acetyl]amino)propanoylUnrated TMT6plex-129 reporter+balance reagent N'-acylated histidineUnrated
(2R,2'R)-3,3'-disulfane-1,2-diylbis(2-aminopropanoic acid)Unrated 3,3'-disulfane-1,2-diylbis(2-azanylpropanoic acid)Unrated 3,3'-dithiobis(2-aminopropanoic acid)Unrated 3,3'-dithiobisalanineUnrated 3,3'-dithiodialanineUnrated beta,beta'-diamino-beta,beta'-dicarboxydiethyldisulfideUnrated beta,beta'-dithiodialanineUnrated bis(alpha-aminopropionic acid)-beta-disulfideUnrated bis(beta-amino-beta-carboxyethyl)disulfideUnrated CysteinylationUnrated cysteinylation (disulfide with free L-cysteine)Unrated dicysteineUnrated L-cystineUnrated MOD_RES S-cysteinyl cysteineUnrated SCysCysUnrated S-cystenyl cystenylUnrated
oxidized proline biotinylated with biotin-LC-hydrazideUnrated
(2R,2'S)-3,3'-sulfanediylbis(2-aminopropanoic acid)Unrated (2R,2'S)-3,3'-thiobis-(2-aminopropanoic acid)Unrated (2R,6S)-2,6-diamino-4-thiaheptanedioic acidUnrated (2R,6S)-meso-lanthionineUnrated (2S)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]sulfanyl]propanoic acidUnrated 3,3'-thiobis-meso-alanineUnrated CROSSLNK Lanthionine (Cys-Ser)Unrated CROSSLNK Lanthionine (Ser-Cys)Unrated cysteine-3-D-alanine thioetherUnrated meso-lanthionineUnrated (R)-S-(2-amino-2-carboxyethyl)-D-cysteineUnrated (R,S)-bis(2-amino-2-carboxyethyl)sulfideUnrated XLNK-SCys-(D)3DhaUnrated
ctermpephsemUnrated homoserineUnrated Homoserine formed from Met by CNBr treatmentUnrated
crosslinked L-isoleucine residueUnrated XlnkIleUnrated
2-ureidopropanoic acidUnrated MOD_RES N-carbamoylalanineUnrated N2CbmAlaUnrated N-carbamoyl-L-alanineUnrated N-carbamylalanineUnrated (S)-2-(carbamoylamino)propanoic acidUnrated
O5-benzyl-L-glutamateUnrated
biantennary (-1 galactose) N4-glycosylated asparagineUnrated
alpha-amidated residueUnrated Amide formation (C terminus)Unrated C1-amidated residueUnrated ctermamideUnrated ResNUnrated
3-sulfanylpropanoyl (N-term and Lys)Unrated
Cys(Ser)Unrated L-cysteine (Ser)Unrated
5x(13)C,1x(15)N labeled L-methionine sulfoxideUnrated
1x(13)C,3x(2)H C(6)-labeled L-methionine sulfoxideUnrated
CmCOUnrated S-carboxymethyl-L-cysteine sulfoxideUnrated
(4-methylpiperazin-1-yl)acetylUnrated iTRAQ4plex-116 reporter+balance reagent acylated residueUnrated
N-methylated serineUnrated
2-[1,3-bisazanyl-3-oxopropyl]-1,3-thiazole-4-carboxylic acidUnrated 2-[(1S)-1,3-diamino-3-oxopropyl]-1,3-thiazole-4-carboxylic acidUnrated CROSSLNK Thiazole-4-carboxylic acid (Asn-Cys)Unrated L-asparagine thiazole-4-carboxylic acidUnrated
Cl1TrpUnrated monochlorinated L-tryptophanUnrated
2-azanylbutanedioic acidUnrated (2S)-2-aminobutanedioic acidUnrated aminosuccinic acidUnrated deamidated L-asparagineUnrated dNAsnUnrated L-aspartic acidUnrated MOD_RES Deamidated asparagineUnrated
D-SerUnrated D-serineUnrated (R)-2-amino-3-hydroxypropanoic acidUnrated
4x(13)C labeled N6-succinyl-L-lysineUnrated
trans-peptidyl-L-prolineUnrated
(4-methylpiperazin-1-yl)acetylUnrated iTRAQ114YUnrated iTRAQ4plex-114 reporter+balance reagent O4'-acylated tyrosineUnrated
8a-FMNResUnrated 8alpha-FMN modified residueUnrated
cysTMT6plex-127 reporter+balance reagent cysteine disulfideUnrated S-(2-{3-[2-(2,6-dimethylpiperidin-1-yl)acetamido]propanamido}ethyl)sulfanylUnrated
(2S)-5-carbamimidamido-2-(dimethylamino)pentanoic acid [tautomer]Unrated (2S)-5-[(diaminomethylidene)amino]-2-(dimethylamino)pentanoic acidUnrated MOD_RES N2,N2-dimethylarginineUnrated N2,N2-dimethylarginineUnrated N2,N2-dimethyl-L-arginineUnrated N(alpha),N(alpha)-dimethylarginineUnrated
1-methylpyrrolidine-2-carboxylic acidUnrated hygric acidUnrated MOD_RES N-methylprolineUnrated NMeProUnrated N-methylated L-prolineUnrated N-methyl-L-prolineUnrated (S)-1-methylpyrrolidine-2-carboxylic acidUnrated
menadione quinone derivative - site CUnrated
4-thiazolidinecarboxylic acidUnrated thioprolineUnrated
2,6-dimethyl-1-methylidenepiperidiniumUnrated cysTMT6plex-130 reporter fragmentUnrated TMT6plex-130 reporter fragmentUnrated
GSIGlyUnrated LIPID GPI-like-anchor amidated glycineUnrated N-glycyl-glycosylsphingolipidinositolethanolamineUnrated
2-[1-amino-2-hydroxyethyl]-1-carboxymethyl-1-imidazolin-5-oneUnrated (2-[(1R)-1-amino-2-hydroxyethyl]-5-oxo-4,5-dihydro-1H-imidazol-1-yl)acetic acidUnrated 4-methylidene-imidazole-5-one (MIO) active siteUnrated CROSSLNK 5-imidazolinone (Ser-Gly)Unrated green fluorescent protein chromophoreUnrated L-serine 5-imidazolinone glycineUnrated para-hydroxybenzylidene-imidazolidinone chromophoreUnrated seryl-5-imidazolinone glycineUnrated
phosphate/sulphate adduct of proteinsUnrated
(2S)-2-([(4-[(2S)-2-amino-2-carboxyethyl]-1H-imidazol-1-yl)methyl]amino)-4-(methylsulfanyl)butanoic acidUnrated N-[(L-histidin-1'-yl)methyl]-L-methionineUnrated N-[(L-histidin-1'-yl)methyl]-L-methionine (fMet)Unrated
ModHisUnrated modified L-histidine residueUnrated
deaminated residueUnrated
oleoylated residueUnrated
(2S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acidUnrated 3,5-diiodo-L-tyrosineUnrated 3',5'-diiodo-L-tyrosineUnrated 3,5-diiodotyrosineUnrated DITUnrated iodogorgoic acidUnrated MOD_RES DiiodotyrosineUnrated
hydroxylated prolineUnrated HyProUnrated
1-aminopropane-1,3-dicarboxylic acidUnrated 2-aminoglutaric acidUnrated 2-azanylpentanedioic acidUnrated (2S)-2-aminopentanedioic acidUnrated alpha-aminoglutaric acidUnrated GluUnrated glutaminic acidUnrated L-glutamic acidUnrated L-glutamic acid residueUnrated
L-threonine methyl esterUnrated methyl (2S,3R)-2-amino-3-hydroxybutanoateUnrated methyl L-threoninateUnrated MOD_RES Threonine methyl esterUnrated
iodouridine monophosphate derivatized tyrosineUnrated
(2R)-2-amino-3-[(phosphonooxy)sulfinyl]propanoic acidUnrated cysteine sulfinic phosphoryl esterUnrated L-cysteine sulfinyl phosphateUnrated

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