Selected DIDEO Terms — English (DIDEO)

Selected terminology labels for DIDEO. Original publisher/project: Drug-drug Interaction and Drug-drug Interaction Evidence Ontology; credited creators: Anuj Shah; Dan Malone; Jessica Tay-Sontheimer; Jingjing Yu; Jodi Schneider; Philip E. Empey; Richard D. Boyce; William R. Hogan; Mathias Brochhausen. Original source: https://purl.obolibrary.org/obo/dideo.owl; actual download: https://raw.githubusercontent.com/DIDEO/DIDEO/master/dideo.owl; official project record: https://obofoundry.org/ontology/dideo.html. Retrieved 2026-11-07. Version: http://purl.obolibrary.org/obo/dideo/release/2023-10-16/dideo.owl; 2023-10-16. Original artifact SHA-256: 1f4da6b6183d897f972890fac672ef637234da6749ba4db233887439ce59ee1b. Original and public license: CC-BY-4.0; license evidence is embedded in that exact artifact: http://creativecommons.org/licenses/by/4.0/. Source IDs and individual source citations are preserved. Languages: English; explicit tags are retained; untagged English labels are inferred from the OLS language index, with this inference retained in private source notes. No nationality, jurisdiction or cross-language equivalence is inferred. Only active own-project owl:Class primary labels and explicit exact synonyms are included. Deprecated classes, general alternative labels, external namespaces, definitions, relationships and imports are excluded. This is a selected subset, not the complete ontology. Semantic review is ongoing; the resource library does not claim project authorization or endorsement.

Curator: Morgan Reed

English
drug-drug interaction management optionUnrated
chlorzoxazone 6-hydroxylationUnrated
reported drug-drug interactionUnrated
drug-drug interactionUnrated
evidence information from p-glycoprotein transport protein identification experiment using overexpressed cell linesUnrated
evidence information from CYP450 recombinant drug metabolism identification experiment using antibody inhibitorsUnrated
clearance measurement datumUnrated
transgenic animal hepatocyte populationUnrated
drug-drug interaction description from drug package insertUnrated
evidence information from chemical analytic characterization of materialUnrated
clinically relevant potential drug-drug interactionUnrated
metabolic potential drug-drug interactionUnrated
area under the curve ratioUnrated
foldUnrated
HBG BC2 cellUnrated
evidence information from CYP450 human microsome drug metabolism identification experimentUnrated
observational data item about drug-drug interactionUnrated
renal clearance ratioUnrated
clinical studyUnrated
human liver S9 fractionUnrated
coumarin 7-hydroxylationUnrated
evidence information from OATP1B3 inhibition experimentUnrated
evidence information from OATP1B1 inhibition experimentUnrated
hepatic clearance ratioUnrated
evidence information from OATP1B3 transport protein identification experimentUnrated
drug maximum concentration measurement datumUnrated
evidence information from p-glycoprotein inhibition experiment using overexpressed cell linesUnrated
dextromethorphan O-demethylationUnrated
evidence data itemUnrated
midazolam 1'-hydroxylationUnrated
pharmacokinetic parameter ratio directionalityUnrated
E. coli recombinant protein production host cellUnrated
evidence information from OATP1B1 transport protein identification experimentUnrated
estradiol glucuronosylationUnrated
freshly isolated human hepatocyte populationUnrated
evidence information from observational studyUnrated
CHO transfected cellUnrated
baculovirus-insect recombinant protein production host cellUnrated
drug bioavailability assayUnrated
precipitant drug roleUnrated
data item about biological processUnrated
evidence information from CYP450 human microsome drug metabolism identification experiment using antibody inhibitorsUnrated
evidence information from observation-based reportUnrated
evidence information from drug metabolism identification experimentUnrated
material entity participant in drug-drug interactionUnrated
evidence information from clinical studyUnrated
evidence information from observational pharmacokinetic studyUnrated
evidence information from CYP450 recombinant drug metabolism identification experiment using chemical inhibitorsUnrated
drug-drug interaction descriptionUnrated
Hep G2 transfected cellUnrated
information about increase of pharmacokinetic area under the curveUnrated
absorbabilityUnrated
percentage value specificationUnrated
metabolism induction potential drug-drug interactionUnrated
293 transfected cellUnrated
drug package insertUnrated
Hep G2 cellUnrated
evidence information from an observation-based case-report of a drug interactionUnrated
time to maximum drug concentration ratioUnrated
evidence material informationUnrated
evidence information from drug metabolism induction experimentUnrated
evidence information from p-glycoprotein transport protein identification experimentUnrated
evidence information content entityUnrated
cryopreserved human hepatocyte populationUnrated
drug package AUC informationUnrated
metabolism inhibition potential drug-drug interactionUnrated
drug-drug interaction description from FDA label informationUnrated
pharmacokinetic parameter ratioUnrated
drug-drug interaction evidenceUnrated
bufuralol 1'-hydroxylationUnrated
evidence information from genotyped pharmacokinetic trialUnrated
absorbability measurement datumUnrated
evidence information from observation-based adverse drug event reportUnrated
evidence information from drug transport protein induction experimentUnrated
evidence information from pharmacokinetic trialUnrated
data item from extrapolationUnrated
drug maximum concentration ratioUnrated
omeprazole 5-hydroxylationUnrated
pharmacokinetic parameter ratio decreaseUnrated
evidence information from parallel groups drug-drug interaction clinical trial'Unrated
diclofenac 4'-hydroxylationUnrated
efflux ratioUnrated
human intestine S9 fractionUnrated
pharmacokinetic area under curveUnrated
evidence information from OATP1B3 transport protein identification experiment using overexpressed cell linesUnrated
primary total clearance enzyme roleUnrated
pharmacokinetic interaction signalUnrated
narrow therapeutic indexUnrated
paclitaxel 6-alpha hydroxylationUnrated
evidence information from OATP1B3 inhibition experiment using overexpressed cell linesUnrated
evidence information from a publicly reported observation-based adverse drug event reportUnrated
human liver cytosolic fractionUnrated
net flux ratioUnrated
public adverse event reporting databaseUnrated
bioavailabilityUnrated
half-life ratioUnrated
evidence information from p-glycoprotein inhibition experimentUnrated
evidence information from non-randomized drug-drug interaction clinical trialUnrated
U.S. Food and Drug Administration drug labelUnrated
number of liver donorsUnrated

Next 100 concepts